BDBM50424972 CHEMBL2316143::US9409845, Table 1, Compound 4: (2E,6E)-2-(3,5-dimethoxybenzylidene)-6-(2-fluorobenzylidene)cyclohexanone

SMILES COc1cc(OC)cc(\C=C2/CCC\C(=C/c3ccccc3F)C2=O)c1

InChI Key InChIKey=CLEKNGMKRNGHMK-YAUBYZHOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50424972   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424972(CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of EGFR cytoplasmic domain (amino acids 645 to 1186) (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphory...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Soochow University

Curated by ChEMBL
LigandPNGBDBM50424972(CHEMBL2316143 | US9409845, Table 1, Compound 4: (2...)
Affinity DataIC50:  2.17E+3nMT: 2°CAssay Description:The kinase activity of EGFR was detected according to time-resolved fluorescence detection technology to evaluate automatic phosphorylation levels. T...More data for this Ligand-Target Pair
In DepthDetails US Patent