BDBM50425046 CHEMBL2312571::US9402842, 23

SMILES COC(=O)CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1

InChI Key InChIKey=WPRKQIRWRMVZPA-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425046   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50425046(CHEMBL2312571 | US9402842, 23)
Affinity DataIC50:  1.80E+4nMpH: 7.5 T: 2°CAssay Description:A 5′-[32P]-labeled single-stranded DNA oligonucleotide containing a 3′-phosphotyrosine (N14Y) was generated as described by Dexheimer et ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50425046(CHEMBL2312571 | US9402842, 23)
Affinity DataEC50: >4.45E+4nMAssay Description:Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue Research Foundation

US Patent
LigandPNGBDBM50425046(CHEMBL2312571 | US9402842, 23)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed