BDBM50425477 (E)-8-(4-Chlorostyryl)caffeine (4a)::CHEMBL2313284

SMILES Cn1c(\C=C\c2ccc(Cl)cc2)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=RQLGXOPACNRPQG-RMKNXTFCSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50425477   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50425477((E)-8-(4-Chlorostyryl)caffeine (4a) | CHEMBL231328...)
Affinity DataKi:  141nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM50425477((E)-8-(4-Chlorostyryl)caffeine (4a) | CHEMBL231328...)
Affinity DataKi:  169nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50425477((E)-8-(4-Chlorostyryl)caffeine (4a) | CHEMBL231328...)
Affinity DataIC50:  430nMAssay Description:Inhibition of human MAOB after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50425477((E)-8-(4-Chlorostyryl)caffeine (4a) | CHEMBL231328...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MAOA after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed