BDBM50425734 CHEMBL2316542

SMILES Cc1cccc(C)c1OCCSc1nc2ccccc2[nH]1

InChI Key InChIKey=VFDZGOPEFRPFRE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425734   

TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50425734(CHEMBL2316542)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BF3 site of androgen receptor in human LNCAP cells expressing ARR2PB assessed as reduction in PSA level after 3 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50425734(CHEMBL2316542)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of BF3 site of androgen receptor in human LNCAP cells expressing ARR2PB after 3 days by eGFP transcriptional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50425734(CHEMBL2316542)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of BF3 site of androgen receptor in enzalutamide-resistant human LNCAP cells assessed as reduction in PSA level after 3 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed