BDBM50426337 CHEMBL1233659

SMILES OC(=O)c1ccc2[nH]c(C3C(=O)Nc4c3cccc4Br)c(N=O)c2c1

InChI Key InChIKey=ZVQKIVSQCORITQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50426337   

LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Sus scrofa)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetCyclin-dependent kinase 5(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Sus scrofa)
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed