BDBM50426838 CHEMBL2323356

SMILES CCOc1ccc(\C=N\NC(=O)CN2CCC(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=PZUITVNJLUHHRJ-JJIBRWJFSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50426838   

TargetCholinesterase(Equus caballus (Horse))
Baskent University

Curated by ChEMBL
LigandPNGBDBM50426838(CHEMBL2323356)
Affinity DataKi:  3.15E+4nMAssay Description:Competitive inhibition of equine BuChE by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Baskent University

Curated by ChEMBL
LigandPNGBDBM50426838(CHEMBL2323356)
Affinity DataKi:  5.08E+4nMAssay Description:Uncompetitive inhibition of human recombinant AChE at 20 to 40 uM by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Baskent University

Curated by ChEMBL
LigandPNGBDBM50426838(CHEMBL2323356)
Affinity DataKi:  8.38E+4nMAssay Description:Noncompetitive inhibition of human recombinant AChE at 60 to 100 uM by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Baskent University

Curated by ChEMBL
LigandPNGBDBM50426838(CHEMBL2323356)
Affinity DataIC50:  5.31E+4nMAssay Description:Inhibition of human recombinant AChE measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
Baskent University

Curated by ChEMBL
LigandPNGBDBM50426838(CHEMBL2323356)
Affinity DataIC50:  6.73E+4nMAssay Description:Inhibition of equine BuChE measured for 1 min by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed