BDBM50426887 CHEMBL2323695

SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(CCCC(=O)NC(C)(C)C(=O)N2CCNCC2)cc1C

InChI Key InChIKey=HZIRWWOSGYBPSU-RHBSMATHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426887   

TargetSodium/glucose cotransporter 2(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426887(CHEMBL2323695)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426887(CHEMBL2323695)
Affinity DataIC50:  11nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426887(CHEMBL2323695)
Affinity DataIC50:  371nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Rattus norvegicus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50426887(CHEMBL2323695)
Affinity DataIC50:  22nMAssay Description:Inhibition of rat SGLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed