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BDBM50427212 (2S,3R)-2,3-Dihydroxysuccinic Acid::CHEMBL225983::Meso-Tartrate

SMILES: O[C@@H]([C@@H](O)C(O)=O)C(O)=O

InChI Key: InChIKey=FEWJPZIEWOKRBE-XIXRPRMCSA-N

Data: 3 IC50

PDB links: 59 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427212   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D-Amino Acid Oxidase (DAAO)


(Homo sapiens (human))
BDBM50427212
PNG
((2S,3R)-2,3-Dihydroxysuccinic Acid | CHEMBL225983 ...)
Show SMILES O[C@@H]([C@@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2+
PDB
MMDB

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KEGG

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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a>1.00E+7n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by colorimetric assay


J Med Chem 56: 1894-907 (2013)

More data for this
Ligand-Target Pair
D-Aspartate Oxidase (DDO)


(Homo sapiens (human))
BDBM50427212
PNG
((2S,3R)-2,3-Dihydroxysuccinic Acid | CHEMBL225983 ...)
Show SMILES O[C@@H]([C@@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2+
KEGG

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

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Article
PubMed
n/an/a 3.92E+6n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal His-tagged DDO expressed in Escherichia coli BL21(DE3) using D-aspartate as substrate by colorimetric assa...


J Med Chem 56: 1894-907 (2013)

More data for this
Ligand-Target Pair
Serine racemase


(Homo sapiens)
BDBM50427212
PNG
((2S,3R)-2,3-Dihydroxysuccinic Acid | CHEMBL225983 ...)
Show SMILES O[C@@H]([C@@H](O)C(O)=O)C(O)=O
Show InChI InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
n/an/a 2.82E+6n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal His-tagged serine racemase expressed in Escherichia coli BL21(DE3) using L-serine as substrate after 10 mi...


J Med Chem 56: 1894-907 (2013)

More data for this
Ligand-Target Pair