BDBM50427905 CHEMBL2326085

SMILES CCN(CC)CC[C@](N)(CCCCB(O)O)C(O)=O

InChI Key InChIKey=PTSLRKWVFCQFLK-GFCCVEGCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50427905   

TargetArginase-2, mitochondrial(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL
LigandPNGBDBM50427905(CHEMBL2326085)
Affinity DataIC50:  934nMAssay Description:Inhibition of human Arg2 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-2, mitochondrial(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL
LigandPNGBDBM50427905(CHEMBL2326085)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant fully active truncated form of arginase 2 overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL
LigandPNGBDBM50427905(CHEMBL2326085)
Affinity DataIC50:  270nMAssay Description:Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArginase-1(Homo sapiens (Human))
Institutes For Pharmaceutical Discovery

Curated by ChEMBL
LigandPNGBDBM50427905(CHEMBL2326085)
Affinity DataIC50:  520nMAssay Description:Inhibition of human recombinant full length Arg1 using L-arginine as substrate assessed as urea level after 1 hr by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed