BDBM50428706 CHEMBL2333138::US9884828, 2-136
SMILES NC(=O)c1nnc2cc(ccc2c1NCCCO)-c1ccncc1
InChI Key InChIKey=YAGKSVSVQYJXKY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50428706
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Imago Pharmaceuticals
US Patent
Imago Pharmaceuticals
US Patent
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:Compounds as described herein (compounds of Formula I, e.g., compounds of the above Examples) are tested for their in vitro kinase activities using v...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Imago Pharmaceuticals
US Patent
Imago Pharmaceuticals
US Patent
Affinity DataIC50: 121nMAssay Description:Inhibition of wild type GST-tagged LRRK2 (970 to 2527 amino acid residues) (unknown origin) assessed as inhibition of biotinylated-LRRKtide phosphory...More data for this Ligand-Target Pair