BDBM50428866 CHEMBL2331783

SMILES Fc1cc(NS(=O)(=O)c2ccc(Cl)cc2Cl)ccc1Oc1cncc(Cl)c1

InChI Key InChIKey=IGYVYFSWBONPAC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428866   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50428866(CHEMBL2331783)
Affinity DataIC50:  36nMAssay Description:Displacement of [3H]-rosiglitazone from GST-tagged PPARgammaLBD (unknown origin) after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50428866(CHEMBL2331783)
Affinity DataEC50:  1.00E+3nMAssay Description:Transactivation of GAL4 DBD-fused human PPARgamma-LBD expressed in HEK293 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed