BDBM50429933 CHEMBL2334255::US10709688, Example 2

SMILES OC(=O)CCCOc1ccccc1-c1cc(-c2ccccc2)n(n1)-c1ccc(Br)cc1

InChI Key InChIKey=WXZVIQMWLYGTHW-UHFFFAOYSA-N

Data  4 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50429933   

TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataKd:  2.11E+3nMAssay Description:Binding affinity to human FABP3 expressed in Escherichia coli BL21 (DE3) at 16 uM by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to human FABP3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Okayama University 1-1-1

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataIC50:  5.64E+3nMAssay Description:Inhibition of human FABP4 by 8-anilino-1-naphthalenesulfonic acid based fluorescence displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Okayama University 1-1-1

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataKd:  2.33E+3nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataIC50:  730nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
TargetFatty acid-binding protein, adipocyte(Homo sapiens (Human))
Okayama University 1-1-1

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataIC50:  5.64E+3nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataKd:  1.25E+3nMAssay Description:A Nunc black plate was used as a 96-well plate for the purpose of measurement, and to each well was added 40 μL of sodium phosphate buffer and a...More data for this Ligand-Target Pair
TargetFatty acid-binding protein, heart(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50429933(CHEMBL2334255 | US10709688, Example 2)
Affinity DataIC50:  733nMAssay Description:Inhibition of human FABP3 by 8-anilino-1-naphthalenesulfonic acid based fluorescence displacement assayMore data for this Ligand-Target Pair