BDBM50430367 CHEMBL2333909

SMILES COc1ccc(C[C@H](N)c2nc3ccc(cc3c(=O)[nH]2)-c2cn[nH]c2)cc1

InChI Key InChIKey=IFSJHRROANUFFS-KRWDZBQOSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50430367   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of MRCKalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50:  16nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50430367(CHEMBL2333909)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed