BDBM50431165 2-(3-hydroxyphenyl)-4H-chromen-4-one (2)::CHEMBL147552::NSC-22356

SMILES Oc1cccc(c1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=ISZWRZGKEWQACU-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431165   

TargetAmine oxidase [flavin-containing] B(Human)
Birla Institute of Technology

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataKi:  800nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
Birla Institute of Technology

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataKi:  3.02E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Universiti Teknologi Mara

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  3.47E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed