BDBM50431165 2-(3-hydroxyphenyl)-4H-chromen-4-one (2)::CHEMBL147552::NSC-22356

SMILES Oc1cccc(c1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=ISZWRZGKEWQACU-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431165   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Birla Institute Of Technology

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataKi:  800nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Birla Institute Of Technology

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataKi:  3.02E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu

Curated by ChEMBL
LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara

LigandPNGBDBM50431165(2-(3-hydroxyphenyl)-4H-chromen-4-one (2) | CHEMBL1...)
Affinity DataIC50:  3.47E+4nMpH: 6.8Assay Description:The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed