BDBM50431630 KRX-0401::PERIFOSINE

SMILES CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1

InChI Key InChIKey=SZFPYBIJACMNJV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50431630   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  4.34E+4nMAssay Description:Inhibition of human Akt1 PH domain using AKTide-2T as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  50nMAssay Description:Inhibition of UCHL3 (unknown origin) assessed as reduction in RAD51 deubiquitination incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
University Of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Akt phosphorylation in human insulin-stimulated A549 cells incubated for 2 hrs prior to insulin-induction measured after 30 mins by ELI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed