BDBM50433411 CHEMBL2380648

SMILES CC(C)(C)N1CCN(CC1)c1ccc(nc1)N1CCN(C(=O)N[C@H]2C3CC4CC2C[C@](C4)(C3)C(N)=O)c2ccccc12

InChI Key InChIKey=RZUKTDWPBQOSBE-PQFSURCISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433411   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  7nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433411(CHEMBL2380648)
Affinity DataIC50:  6nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed