BDBM50433562 CHEMBL1818538::Nutlin-1
SMILES COc1ccc(C2=NC(C(N2C(=O)N2CCN(CC2)C(C)=O)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
InChI Key InChIKey=IYDMGGPKSVWQRT-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50433562
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant p53 protein binding to recombinant human MDM2 by surface plasmon resonance methodMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Jss Academy Of Higher Education And Research
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair