BDBM50434337 CHEMBL2386727::US9181275, 1

SMILES CC1=C(SC2=NCc3ccccc3CN12)c1ccc(OCCCN2CCC[C@H]2CO)cc1

InChI Key InChIKey=KCNBMJDSPWNQQE-QHCPKHFHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434337   

TargetHistamine H3 receptor(Rattus norvegicus (rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434337(CHEMBL2386727 | US9181275, 1)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50434337(CHEMBL2386727 | US9181275, 1)
Affinity DataKi:  0.0320nM ΔG°:  -14.3kcal/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
In DepthDetails US Patent