BDBM50434485 CHEMBL2385543

SMILES Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cccnc3)C(=O)c2o1)N1CCNCC1

InChI Key InChIKey=WCQPZKBEGJASRO-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50434485   

TargetTestis-specific serine/threonine-protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of TSSK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  22nMAssay Description:Inhibition of MK2 (unknown origin) phosphorylation using TAMRA labeled peptide as substrate incubated 30 mins before substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >1.20E+4nMAssay Description:Inhibition of MST2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of IGF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of CAMK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of IKKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of AKT1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CSNK1D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of PLK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50434485(CHEMBL2385543)
Affinity DataIC50: >1.80E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed