BDBM50434662 CHEMBL2387475

SMILES Fc1cccc(F)c1-c1cnc2[nH]cc(NC(=O)c3cnn4ccc(OCC5CCNCC5)nc34)c2c1

InChI Key InChIKey=TWPUKPNAJWOXOF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434662   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50434662(CHEMBL2387475)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of PIM1 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50434662(CHEMBL2387475)
Affinity DataKi:  0.0620nMAssay Description:Inhibition of PIM3 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50434662(CHEMBL2387475)
Affinity DataKi:  0.650nMAssay Description:Inhibition of PIM2 (unknown origin) using FAM-pimtide as substrate after 90 mins by spectrophotometry in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed