BDBM50434762 CHEMBL2385818

SMILES CC(C)C[C@H](NC(=O)[C@H](C)n1ccc2ncccc2c1=O)B(O)O

InChI Key InChIKey=IXCMFUUHZQXNIL-FZMZJTMJSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50434762   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50434762(CHEMBL2385818)
Affinity DataKi:  1.34E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as Suc-Leu-Leu-Val-Tyr-AMC substrate hydrolysis after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50434762(CHEMBL2385818)
Affinity DataKi:  1.34E+3nMAssay Description:Inhibition of human 20S proteasome chymotrypsin like activity using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured over 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50434762(CHEMBL2385818)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed