BDBM50435190 CHEMBL2392926

SMILES Cc1nc(nc(NC[C@H](NCCCCc2ccc(cc2)C#N)c2ccccc2)c1Cl)-c1ccc(Cl)cn1

InChI Key InChIKey=PZULZLKLPURNST-SANMLTNESA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435190   

TargetMethionine aminopeptidase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435190(CHEMBL2392926)
Affinity DataEC50:  520nMAssay Description:Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50435190(CHEMBL2392926)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed