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BDBM50436108 CHEMBL2397441

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2ccc3cccc3cc2)c1

InChI Key: InChIKey=RMKKIBKWWZGSPJ-IOTSYWNANA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436108   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 2 (SGLT2)


(Homo sapiens (Human))
BDBM50436108
PNG
(CHEMBL2397441)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2ccc3cccc3cc2)c1
Show InChI InChI=1/C23H24O5/c24-13-19-20(25)21(26)22(27)23(28-19)18-6-1-3-15(12-18)11-14-7-9-16-4-2-5-17(16)10-8-14/h1-10,12,19-27H,11,13H2/t19-,20-,21+,22-,23+/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 99n/an/an/an/an/an/a



Astellas Pharmaceutical Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-methyl-alpha-D-glucopyranoside accumulation


Bioorg Med Chem 21: 3934-48 (2013)


Article DOI: 10.1016/j.bmc.2013.03.067
BindingDB Entry DOI: 10.7270/Q2ZC848C
More data for this
Ligand-Target Pair