BDBM50436686 CHEMBL2398475

SMILES CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@@H](O)C1

InChI Key InChIKey=YPBSIJVXMPPDCG-GPJJJBLTSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436686   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50436686(CHEMBL2398475)
Affinity DataKi:  0.940nMAssay Description:Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 mins by competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50436686(CHEMBL2398475)
Affinity DataIC50:  8.80nMAssay Description:Binding affinity to recombinant human His-tagged MDM2 (1 to 118 amino acids) using p53-based PMDM6-F as probe after 15 to 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed