BDBM50437017 CHEMBL2402905

SMILES CCNC(=O)C(C1CCN(CC1)c1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1F)c1ccccc1

InChI Key InChIKey=KUIGPXCNMWLIGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437017   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50437017(CHEMBL2402905)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]PYY from NPY-Y2 receptor in human KAN-TS cell membranes after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50437017(CHEMBL2402905)
Affinity DataIC50:  13nMAssay Description:Inhibition of MTP (unknown origin)-mediated triglyceride transfer from donor to acceptor vesicles preincubated for 5 mins followed by enzyme addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed