BDBM50437991 CHEMBL2409450

SMILES Cc1cccc(c1)C(=O)n1nc(C#N)c2ccccc12

InChI Key InChIKey=KRFSMLDUZFVINX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50437991   

TargetChymotrypsinogen B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50437991(CHEMBL2409450)
Affinity DataIC50:  66nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50437991(CHEMBL2409450)
Affinity DataIC50:  7nMAssay Description:Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 secs for 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50437991(CHEMBL2409450)
Affinity DataIC50:  7nMAssay Description:Inhibition of human neutrophil elastase using N-methylsuccinyl-Ala-Ala-Pro-Val-7-amino-4-methylcoumarin as substrate measured every 30 seconds for 10...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed