BDBM50438321 CHEMBL2408731

SMILES Cc1nn(C)cc1-c1cnc(N)c2oc(cc12)-c1csc2cnccc12

InChI Key InChIKey=ZFWMKNDHIGULFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438321   

TargetAurora kinase B(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed