BDBM50439805 CHEMBL2419692::US9227982, 2

SMILES Fc1ccc(CCC(=O)N(Cc2cccs2)Cc2nc3CCOCc3c(=O)[nH]2)cc1

InChI Key InChIKey=WMOFKDNPUXQKFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439805   

TargetPoly [ADP-ribose] polymerase tankyrase-2 [959-1164](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439805(CHEMBL2419692 | US9227982, 2)
Affinity DataIC50:  78nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439805(CHEMBL2419692 | US9227982, 2)
Affinity DataIC50:  483nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1 [1112-1317](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439805(CHEMBL2419692 | US9227982, 2)
Affinity DataIC50:  299nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent