BDBM50439808 CHEMBL2419717::US9227982, 12

SMILES O=C(CCc1cccnc1)N(Cc1cccs1)Cc1nc2CCOCc2c(=O)[nH]1

InChI Key InChIKey=WEHBTALITPPXOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439808   

TargetPoly [ADP-ribose] polymerase tankyrase-2 [959-1164](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439808(CHEMBL2419717 | US9227982, 12)
Affinity DataIC50:  1.01E+4nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439808(CHEMBL2419717 | US9227982, 12)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1 [1112-1317](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM50439808(CHEMBL2419717 | US9227982, 12)
Affinity DataIC50:  1.46E+4nMT: 2°CAssay Description:The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...More data for this Ligand-Target Pair
In DepthDetails US Patent