BDBM50440967 CHEMBL2431993::US10196373, Compound BP2-061

SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1)Cc1ccccc1C(F)(F)F

InChI Key InChIKey=GFASCHAWPQEYTQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440967   

TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The Governing Council Of The University Of Toronto

US Patent
LigandPNGBDBM50440967(CHEMBL2431993 | US10196373, Compound BP2-061)
Affinity DataKi:  1.80E+3nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSignal transducer and activator of transcription 1-alpha/beta(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50440967(CHEMBL2431993 | US10196373, Compound BP2-061)
Affinity DataIC50:  5.80E+3nMAssay Description:Binding affinity to Stat1 (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The Governing Council Of The University Of Toronto

US Patent
LigandPNGBDBM50440967(CHEMBL2431993 | US10196373, Compound BP2-061)
Affinity DataIC50:  2.80E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed