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BDBM50441973 CHEMBL2440218

SMILES: COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C

InChI Key: InChIKey=UXSFANIQULVRMS-UHFFFAOYSA-N

Data: 1 KI  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441973   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytohesin-2


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
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CHEMBL
MMDB
PC cid
PC sid
PDB
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PDB
Article
PubMed
1.61E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
G-protein coupled receptor 120


(Homo sapiens)
BDBM50441973
PNG
(CHEMBL2440218)
Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C
Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

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CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

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Article
PubMed
n/an/an/an/a<3.16E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Agonist activity at human FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR


Bioorg Med Chem Lett 24: 3100-3 (2014)

More data for this
Ligand-Target Pair