BindingDB logo
myBDB logout

BDBM50441977 CHEMBL2440208

SMILES: Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1

InChI Key: InChIKey=GLDVWHQVGHPIFH-UHFFFAOYSA-N

Data: 1 KI  1 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441977   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
3.72E+6n/an/an/an/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cytohesin-2


(Homo sapiens)
BDBM50441977
PNG
(CHEMBL2440208)
Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
n/an/an/a 5.00E+5n/an/an/an/an/a



UMR 5247

Curated by ChEMBL


Assay Description
Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis


J Med Chem 56: 8497-511 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)