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BDBM50442524 SR-41319::Skelid::TILUDRONIC ACID::Tiludronate

SMILES: OP(O)(=O)C(Sc1ccc(Cl)cc1)P(O)(O)=O

InChI Key: InChIKey=DKJJVAGXPKPDRL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50442524
PNG
(SR-41319 | Skelid | TILUDRONIC ACID | Tiludronate)
Show SMILES OP(O)(=O)C(Sc1ccc(Cl)cc1)P(O)(O)=O
Show InChI InChI=1S/C7H9ClO6P2S/c8-5-1-3-6(4-2-5)17-7(15(9,10)11)16(12,13)14/h1-4,7H,(H2,9,10,11)(H2,12,13,14)
PDB

UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.05E+4n/an/an/an/an/an/a



Universit£ degli Studi 'Aldo Moro' di Bari

Curated by ChEMBL


Assay Description
Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate...


Bioorg Med Chem 21: 6456-65 (2013)


Article DOI: 10.1016/j.bmc.2013.08.054
BindingDB Entry DOI: 10.7270/Q2222W7K
More data for this
Ligand-Target Pair