BDBM50443217 CHEMBL3087669

SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(NC(=O)c2c(C)noc2C)c(C)c1

InChI Key InChIKey=CJUSJFAZUSWFLY-KXBFYZLASA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50443217   

TargetHistamine receptor H3(Macaca mulatta (Rhesus macaque))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from recombinant rhesus monkey histamine H3 receptor transfected in CHO cells after 1 hr by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]-methylhistamine from rat histamine H3 receptor (445 amino acid residues) transfected in human 293 cells after 1 hr by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin) after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Canis familiaris)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of canine ERG current transfected in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50443217(CHEMBL3087669)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin) after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed