BDBM50444583 CHEMBL3099716::US9340549, 74
SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)c1cnc(N)c(c1)-c1ncccn1
InChI Key InChIKey=QTAONPFQLNZKSD-XJABCFGWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50444583
Affinity DataIC50: 8.30nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47nMT: 2°CAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of BSEP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >4.85E+4nMAssay Description:Binding affinity to NK1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >4.85E+4nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Antagonistic activity against histamine H3 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: >4.85E+4nMAssay Description:Binding affinity to CCR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.70E+5nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >8.50E+4nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antagonistic activity against histamine H3 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: >4.85E+4nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair