BDBM50445006 CHEMBL3099943

SMILES O[C@H](COc1cc(O)c(Cl)cc1NC(=O)NC1CC1)CN1CCC2(Cc3cc(Cl)ccc3O2)CC1

InChI Key InChIKey=QJAYKDGGKXBVAZ-SFHVURJKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445006   

TargetC-C chemokine receptor type 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445006(CHEMBL3099943)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage inflammatory protein-1 alpha receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50445006(CHEMBL3099943)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]MIP-1alpha from rat CCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed