BDBM50445298 CHEMBL3104229

SMILES O=C1NC(=S)N\C1=C\c1ccc(s1)-c1cccnc1

InChI Key InChIKey=PSQKRXABUNNCAU-UXBLZVDNSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445298   

TargetPerforin-1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50445298(CHEMBL3104229)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human [51Cr]-labelled Jurkat cells assessed as release of [51Cr] preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50445298(CHEMBL3104229)
Affinity DataEC50:  2.77E+4nMAssay Description:Inhibition of wild type recombinant human Top1 expressed in baculovirus infected insect Sf9 cells assessed as decrease in supercoiled pBS(SK+) DNA is...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed