BDBM50446088 CHEMBL3108870

SMILES Fc1ccc(CC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nncs2)cc1Cl

InChI Key InChIKey=DDCAUPBWFJKZDY-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446088   

TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50446088(CHEMBL3108870)
Affinity DataKi:  52nMAssay Description:Competitive inhibition Trypanosoma brucei PFK using fructose-6-phosphate as substrate by Line-weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50446088(CHEMBL3108870)
Affinity DataKi:  240nMAssay Description:Mixed type inhibition Trypanosoma brucei PFK using ATP as substrate by Line-weaver Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma cruzi)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50446088(CHEMBL3108870)
Affinity DataIC50:  172nMAssay Description:Inhibition of Trypanosoma cruzi PFKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent 6-phosphofructokinase(Trypanosoma brucei)
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50446088(CHEMBL3108870)
Affinity DataIC50:  15nMAssay Description:Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed