BDBM50446411 CHEMBL501426

SMILES Oc1ccc(c(O)c1)-c1ccccc1

InChI Key InChIKey=LYXCJGJSIWFKHZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50446411   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50446411(CHEMBL501426)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 15-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50446411(CHEMBL501426)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 12-LO in human PMNL using arachidonic acid preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50446411(CHEMBL501426)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50446411(CHEMBL501426)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed