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BDBM50446558 CHEMBL3110195

SMILES: Nc1ncnc2n(CCCCOP(O)(=O)OP(O)(=O)OC[C@H]3OC(O)[C@H](O)[C@@H]3O)cnc12

InChI Key: InChIKey=QLSSVVPBPOLFQA-OYBGHCQBSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446558   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily M member 2


(Homo sapiens)
BDBM50446558
PNG
(CHEMBL3110195)
Show SMILES Nc1ncnc2n(CCCCOP(O)(=O)OP(O)(=O)OC[C@H]3OC(O)[C@H](O)[C@@H]3O)cnc12
Show InChI InChI=1S/C14H23N5O11P2/c15-12-9-13(17-6-16-12)19(7-18-9)3-1-2-4-27-31(23,24)30-32(25,26)28-5-8-10(20)11(21)14(22)29-8/h6-8,10-11,14,20-22H,1-5H2,(H,23,24)(H,25,26)(H2,15,16,17)/t8-,10-,11-,14?/m1/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



University of Bath

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by wh...


J Med Chem 56: 10079-102 (2013)


Article DOI: 10.1021/jm401497a
BindingDB Entry DOI: 10.7270/Q2CZ38P3
More data for this
Ligand-Target Pair