BDBM50446884 CHEMBL3115282

SMILES OC(=O)CNC(=O)c1c(O)n(Cc2ccccc2C#N)c(=O)n(Cc2ccccc2)c1=O

InChI Key InChIKey=FZWGTWWALUTNKF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446884   

TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446884(CHEMBL3115282)
Affinity DataEC50:  400nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446884(CHEMBL3115282)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed