BDBM50448040 CHEMBL3115496

SMILES Brc1ccc2nc3cc(Nc4ccccc4)ncn3c2c1

InChI Key InChIKey=NXOVFROFMLIDMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448040   

TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448040(CHEMBL3115496)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448040(CHEMBL3115496)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed