BDBM50448044 CHEMBL3115497

SMILES COc1ccc(cc1)-c1cc2nc3ccc(Br)cc3n2cn1

InChI Key InChIKey=LXFDDRLDJDMVTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448044   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448044(CHEMBL3115497)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant wild type ALK catalytic domain (1064 to 1427) (unknown origin) expressed in baculovirus expression system using ARDIYRASFFR...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50448044(CHEMBL3115497)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed