BDBM50448150 CHEMBL3122225

SMILES C[C@@H]1CCCN1C(=O)c1nn(C)c2nc(OCc3ccccn3)ccc12

InChI Key InChIKey=CFGXSLFUPKEOSD-CYBMUJFWSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448150   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448150(CHEMBL3122225)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]-MPEPy from human mGluR5 expressed in HEK293FT cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448150(CHEMBL3122225)
Affinity DataIC50:  2.98E+4nMAssay Description:Negative allosteric modulation of human mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux after 16 to 24 hrs ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed