BDBM50448235 CHEMBL3120758

SMILES Cc1c(Cl)cccc1S(=O)(=O)NC(C)(C)CC(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)C(N)=O

InChI Key InChIKey=JEMYWOKXSQSBLH-LQBDUSRCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448235   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448235(CHEMBL3120758)
Affinity DataIC50:  1nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50448235(CHEMBL3120758)
Affinity DataIC50:  12nMAssay Description:Inhibition of 11beta-HSD1 in mouse liver microsomes using cortisone as substrate after 2 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed