BDBM50449297 CHEMBL3125389
SMILES NC(=O)c1sc(nc1CC(=O)N1CCc2c1cccc2Cl)N1CCOCC1
InChI Key InChIKey=LWUXPHDHNVTIOD-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50449297
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PI3Kgamma after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of human PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human PI3Kbeta after 15 minsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 122nMAssay Description:Inhibition of PI3Kbeta in human PTEN-deficient PC3 cells assessed as Akt phosphorylation at S473More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 277nMAssay Description:Inhibition of human PI3Kdelta after 15 minsMore data for this Ligand-Target Pair