BDBM50450515 CHEMBL4175525

SMILES COc1cc2c(OCCN(C)C)nc3c(ccc4cc5OCOc5cc34)c2cc1OC

InChI Key InChIKey=JNKBJOZJNGEUSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450515   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50450515(CHEMBL4175525)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of recombinant human TDP1 using 5'FAM-AGGATCTAAAAGACTT-BHQ-3' as substrate preincubated for 30 mins followed by substrate addition by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50450515(CHEMBL4175525)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant human TDP1 using 5'-32P-labeled N14Y as substrate after 15 mins by PAGE analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed