BDBM50450624 CHEMBL4176696

SMILES ONC(=O)c1cn(nn1)-c1cc(Cl)ccc1Oc1ccc(F)cc1

InChI Key InChIKey=NXLUFTCWMNFMML-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450624   

TargetHistone deacetylase 8(Blood fluke)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50450624(CHEMBL4176696)
Affinity DataIC50:  504nMAssay Description:Inhibition of Schistosoma mansoni His-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluoro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone deacetylase 8(Human)
University of Strasbourg

Curated by ChEMBL
LigandPNGBDBM50450624(CHEMBL4176696)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human His-thioredoxin-tagged HDAC8 expressed in Escherichia coli BL21 (DE3) cells using Fluor de Lys (R)-HDAC8 as substrate by fluorome...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed