BDBM50452458 CHEMBL4207138

SMILES C[C@H](CO)Nc1nc(N[C@@H]2CC[C@@H](CC2)NC(=O)NC2(CO)CCCC2)c2cc(ccc2n1)-c1cccc(F)c1

InChI Key InChIKey=RMGPQXNQAAUOOB-FOVJLYNBSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452458   

TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452458(CHEMBL4207138)
Affinity DataEC50:  78nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50452458(CHEMBL4207138)
Affinity DataEC50:  120nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed